Recent Publications
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CAR T cells produced in vivo to treat cardiac injury
Science | AAAS
Jan 7, 2022

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In vivo hematopoietic stem cell modification by mRNA delivery
Science | AAAS
Jul 28, 2023

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Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs
Molecular Therapy
Jun 3, 2021

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CD47 peptide-cloaked lipid nanoparticles promote cell-specific mRNA delivery
Molecular Therapy
Mar 13, 2025

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IL7 increases targeted lipid nanoparticle–mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell....
PNAS
Mar 21, 2024

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Rapid receptor internalization potentiates CD7-targeted lipid nanoparticles for efficient mRNA delivery to T cells and in vivo CAR T-cell engineering
bioRxiv
Jan 26, 2026

Latest News
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Congratulations to Alejandra Bahena on her appointment to the Pharmacology T32 Training Grant, which will support her thesis research in the lab!
Jul 30, 2025
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Capstan Therapeutics Acquired by AbbVie for $2.1B
Penn Center for Innovation
Sep 2, 2025
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Capstan Therapeutics Begins Phase 1 Trial of CAR-T Therapy for Autoimmune Disease
Penn Center for Innovation
Jun 11, 2025